Dec 17, 2018 09:36
5 yrs ago
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English term

\"a Small/Mothers Against Decapentaplegic (SMAD) protein\"

English to French Tech/Engineering Biology (-tech,-chem,micro-) differentiation of corneal cells from stem cells
contexte

"NCSCs are produced from embryonic stem (ES) cells, and the method comprises contacting the ES cells with at least one inhibitor of Small/Mothers Against Decapentaplegic (SMAD) protein signaling selected from Noggin, 4-[4-(1,3benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide (SB431542), or a combination of Noggin and SB431542, to induce differentiation of the ES cells into the neural crest stem cells (NCSCs)."

"The one or more inhibitors of SMAD protein signaling may prevent the activation of a TGF-ß receptor. The one or more inhibitors of SMAD protein signaling inhibits one or more SMAD intracellular proteins/transcription factors. The one or more inhibitors of SMAD protein signaling may comprise
Leukemia Inhibitory Factor (LIF), GSK3 inhibitor (CHIR 99021), Compound E (y secretase inhibitor XXI), SB431542, or any combination thereof."

Proposed translations

+1
19 mins
Selected

small/mothers against decapentaplegic (SMAD)

This is the name of the protein.
SMAD = Small/Mothers Against Decapentaplegic
I wouldn't translate it in French
Peer comment(s):

agree B D Finch
14 mins
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4 KudoZ points awarded for this answer.
+1
20 mins

protéine SMAD

ne pas traduire
Peer comment(s):

agree Drmanu49 : www.ipubli.inserm.fr/bitstream/handle/10608/1481/1999_8-9_1039.pdf?sequence... de JM Gauthier - ‎1999 Les protéines Smad et TGFβ: l'heure est à l'intégration… Les membres de la superfamille du. TGFβ (TGFβ1 et les isoformes. TGFβ2 et TGFβ3, activines et B
2 hrs
Merci Drmanu
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Reference comments

33 mins
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